Gastric muscle was isolated and electrical, mechanical recording were done. All of the following statements are true about the recording except –

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Gastric muscle was isolated and electrical, mechanical recording were done. All of the following statements are true about the recording except –

[A]. Tension developed proportional to frequency of spike potential

[B]. Frequency is around 6/min

[C]. Threshold voltage is -50mv

[D]. Tension developed directly proportional to amplitude of spike potential

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[D]. Tension developed directly proportional to amplitude of spike potential
Explanation :-

Basic electrical rhythm (BER) of gastrointestinal smooth muscle

  • Normal gastrointestinal motility results from coordinated contractions of smooth muscle, which in turn derive from two basic patterns of electrical activity across the membranes of smooth muscle cells – slow waves and spike potentials

  • Importantly, slow waves are not action potentials and by themselves do not elicit contractions. Rather, they coordinate or synchronize muscle contractions in the gut by controlling the appearance of a second type of depolarization event – “spike potentials” – which occur only at the crests of slow waves

  • The resting membrane potential of smooth muscle cells is between -50 and -60 mV.

  • Tension does not depend on amplitude it depends on frequency of spike potentials

  • The rate of the BER is about 4/min in the stomach. It is about 12/min in the duodenum and falls to about 8/min in the distal ileum. In the colon, the BER rate rises from about 2/min at the cecum to about 6/min at the sigmoid.

Stimulatory effect of acetylcholine and inhibitory effect of epinephrine on Basic electrical rhythm :
ber

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